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Berghoff, S

F., & Di Trapani, G

The latter sets the stage for subsequent genetic hits that eventually reverse the quiescent cellular phenotype and tilt the cell towards hyperproliferation, as exemplified by the upregulated MYC and E2F targets and other cell cycle genes observed in murine and human leukemic cells, and Myc amplification in murine CLL 69,115,116

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