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KPV is the C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (alpha-MSH)

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2: where I 50 is the concentration of free peptide at 50% inhibition, L 50 is the concentration of FAT at 50% inhibition, P 0 is the concentration of free protein, and K D is calculated from the saturation curve of FAT and TAMRA-LD2 L10D