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Bursitis develops when excessive friction, pressure, or strain causes the bursa to become inflamed
Going barefoot on hard surfaces, wearing flat shoes without support, or spending extended time in worn-out footwear can undermine healing progress even with peptide therapy
This counterintuitive response resolves with dose reduction
Preclinical in vivo models have examined its effects on nitric oxide synthase activity, extracellular matrix protein expression, and actin cytoskeletal dynamics in connective tissue contexts
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