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To fully understand GLP-1RAs effects on bone metabolism in a range of patient groups, particularly regarding osteoporosis and fracture risk management, more randomized controlled studies are necessary (69)

Decreased Food Noise: The persistent mental chatter about your next meal or constant cravings for sweets and snacks often begins to quiet down

Both medication types also cause rapid body composition changes

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5,6 Additionally, high glucose levels negatively impact osteoblast function, contributing to bone defects partly through the production of advanced glycation end-products (AGEs), which upregulates sclerostin, an inhibitor of osteoblast activity