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Debra Houry, acting deputy director of the CDC, in a recent press release

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For someone who cares about energy levels, exercise capacity, or just feeling good day to day, that tradeoff demands some serious scrutiny and consideration

Because the incidence of AEs was greatest during dose escalation, the disparity in total years of exposure between the two trials could potentially dilute the reported rate of AEs in PIONEER 3 compared with PIONEER 12