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Phase II clinical trials in humans showed that AOD-9604 produced statistically significant weight loss compared to placebo over 12 weeks
Hepatic glutathione concentrations directly correlate with liver antioxidant capacity and resilience
In addition to increased secretion of gut peptides, prebiotic treatment improves gut barrier integrity under the conditions of HF feeding and obesity, ultimately reducing circulating LPS 256
The move marks a more aggressive approach for Novo under Chief Executive Mike Doustdar
These findings have moved the field beyond a simple neuronal replacement model
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