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Leptin is a hormone involved in regulating energy balance and appetite, which could imply that increased food intake may contribute to the observed weight gain in peptide-exposed models, which then may increase leptin levels and subdue appetite

Both hormones influence insulin and glucagon secretion, but GLP-1 has stronger effects on weight loss and heart health

[1] [2] Medullary thyroid carcinoma is a rare form of thyroid cancer arising from parafollicular C-cells, accounting for approximately 3% to 4% of all thyroid cancers

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Obviously, theres major limitations to this