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Phthalates and Their Impacts on Human Health

Their functional plasticity, shifting between inflammatory, repair, or anti-inflammatory states, depends on metabolic adaptation and lipid remodeling, including choline uptake and phospholipid reorganization ( 2.1.1 Macrophages and dendritic cells Macrophage functions, such as cytokine and chemokine secretion, phagocytosis, and organelle biogenesis, are intricately linked to membrane phospholipid composition, curvature, and charge ( Figure 3 )

The incidence of serious adverse outcomes, characterized as either DE or LT events, varied between 7% and 28% across the four treatment regimens (refer to Figure 3A)

GHK-Cu drives remodeling and gene-expression signaling