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Graham et al., 2011)
Before AFB 1 can form glucuronide and sulfate conjugates it requires to be hydroxylated
Reducing Inflammation Chronic inflammation in the gastrointestinal (GI) tract is a major contributor to conditions like IBS (irritable bowel syndrome), IBD (inflammatory bowel disease), or gut damage from ibuprofen and naproxen use
Another potential therapeutic, Minocycline is a microglial inhibitor which reduces BBB dysfunction by preventing production of glutamate, matrix metalloproteinases, and the proinflammatory cytokine, IL-1, and increasing the levels of cells responsible for the remyelination of neurons which would be relevant in treating AD [138, 140,141,142]
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