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Computational modeling integrates multi-scale data to construct dynamic networks capable of predicting polarization states

NSL literature pointer PMID 6473858 L-Carnitine laboratory index [PMID: 6473858] National Science Labs indexing note for PMID 6473858: review the PubMed methods, models, and limitations before citing

Additionally, obesity and IR both contribute to -cell dysfunction and apoptosis, mechanistically explained by glucotoxicity and increased immunogenicity (the accelerator hypothesis) or by -cell exhaustion due to increased metabolic demand (the overload hypothesis) [23]

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