OHSS can be both painful and dangerous
As a doctor, theres a lot of burden on your shoulders when you are prescribing something with insufficient evidence, but the patients insist on giving it a try. With no formal approvals surrounding their use from regulatory bodies like the Drugs Controller General of India (DCGI), they are considered off-label treatments
Second, it slows down how fast the kidneys can filter the medication out of the body
GLP-1 Receptor Agonists More and more clinicians are using GLP-1s off-label in people with type 1 diabetes, particularly in those who also have obesity or high insulin requirements, says Mihail Zilbermint, MD, an associate professor of medicine at Johns Hopkins University School of Medicine and the chief of the division of endocrinology, diabetes, and metabolism at Suburban Hospital in Maryland
If using topically, apply at night so your skin can absorb it while you sleep and repair overnight