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Sarcopenia in elderly diabetic patients: role of dipeptidyl peptidase 4 inhibitors

2024 Jun 26;13(13):3729

GLP-1 infusion slows gastric emptying of solid and liquid components of food and alters the distribution of food in the stomach so that a greater proportion of food is retained in the distal stomach (Marathe et al., 2011)

The gradual dose escalation protocol specifically aims to minimize these effects while building therapeutic benefit

In 2012 the method to test the difference between distributions across years was changed to use a Wald test which accounts for the complex survey design