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Similar results were reported in the study of Chen et al., where high TMAO levels increased the expression of tumor necrosis factor- (TNF-) and interleukin-6 (IL-6), but inhibited the expression of anti-inflammatory cytokine interleukin-10 (IL-10), thereby accelerating cellular inflammation in obese mice treated with a Western diet (73)

[1] [7] The FDA-approved prescribing information specifies three anatomical sites for subcutaneous administration: the abdomen, thigh, and upper arm

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However, maintaining a nutritious diet can synergize with the treatment

Obesity is associated with low-grade chronic inflammation in fat tissue