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Unlike oral supplements, an injection delivers vitamin B12 directly into the body without relying on digestive absorption which can be reduced by age, certain medications such as proton pump inhibitors or metformin, or gastrointestinal conditions

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Hydroxocobalamin is the form the NHS uses because it lingers in the body longer than cyanocobalamin, and its pharmacology supports dosing intervals of up to three months once levels are stable

Vitamin B12 deficiency A 21st century perspective. British Journal of General Practice

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