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These drugs work by imitating glucagon-like peptide-1 (GLP-1), a growth hormone that triggers insulin release, reduces blood sugar levels, slows the progress of food along the intestinal track, and stimulates parts of the brain that control craving and satiety
It is not known whether tirzepatide is safe for pregnant and lactating women
Metformin HCl extended-release: the recommended starting dosage of metformin HCl extended-release in XIGDUO XR is 500 mg orally once daily
Methods We used Mendelian randomization to obtain unconfounded estimates
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