Acknowledgements This work has been supported by National Natural Science Foundation of China grants (W2412122, 82470195, 82200208), Natural Science Foundation of Tianjin grants (24JCYBJC00780, 24ZXZSSS00050), State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine grants (QZ 23-6, 23-4), Jin Men Medical Talents of Tianjin (TJSJMYXYC-D2-039), Clinical Oncology Research Fund of CSCO grant (Y-2024AZ(BTK)MS-0040) and Tianjin Key Medical Discipline (Specialty) Construction Project grant (TJYXZDXK-009A)
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Do not self-prescribe high-dose B12 based on non-specific symptoms like fatigue without medical assessment
As a result, the dark spots become less visible or disappear entirely
When the pressure inside the skull rises, whether from excess cerebrospinal fluid, venous sinus stenosis, or other causes, the result is a headache that can mimic migraine in its severity and characteristics