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93 A population of 80 patients who experienced muscle pain in 2 or more extremities within 60 days of starting statin therapy were randomized to 120 mg CoQ10 (60 mg twice daily) or placebo

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Quinlan et al., 2013), complex I and complex III (Venditti et al., 2013) have been shown to be the most important sources of mitochondrial superoxide generation, although significant production of ROS in complex II has recently also been reported (Quinlan et al., 2012)