All TPP-dependent enzymes contain a highly similar TPP-binding domain and its lack in the TKTL1 encoded protein strongly suggests that it is unlikely that TKTL1 is a TPP-dependent protein capable of catalyzing the transketolase reaction
This means your body stops responding as efficiently, and the benefits diminish over time
GSH is a highly effective scavenger of free radicals when combined with a mixture of vitamins C, E, Se, and GPx [111]
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