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Head-to-Head Comparison FDA-Approved Dosing Guidelines Ozempic Dosing: Starting dose: 0.25mg weekly for 4 weeks Increase to 0.5mg weekly Can increase to 1mg, then 2mg weekly based on response Wegovy Dosing: Month 1: 0.25mg weekly Month 2: 0.5mg weekly Month 3: 1mg weekly Month 4: 1.7mg weekly Maintenance: 2.4mg weekly Mounjaro Dosing: The initial dosage of tirzepatide for treatment initiation is 2.5 mg administered SQ once weekly, with available strengths of 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg per 0.5 mL

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PMCID: PMC11646169

doi:10.1016/S0006-8993(97)00648-3 135