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The 25-hydroxyvitamin D 3 1--hydroxylase enzyme is encoded by the CYP27B1 (cytochrome P450 27B1) gene

But certain species produce potent toxic secondary metabolites called mycotoxins, and these compounds are in a different category entirely

Alveolar and serum oxidative stress in ventilator-associated pneumonia

Based on prior reports linking mitochondrial protein stability to a short fragment within the cyclic structural domain of SLC25A39 (amino acids 7286) that mediates glutathione (GSH) response and recruits SLC25A39 to AFG3L2 for proteolysis, we generated a deletion mutant lacking this fragment (aa72-86), confirmed by Sanger sequencing (Fig

LPO, IEC death and proliferation were comparable between Gpx4 +/IEC and WT mice (Supplementary Fig