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Studies have found that high NNMT expression promotes the release of inflammatory factors in adipose tissue, and NNMTi can effectively alleviate adipose inflammation and improve the microenvironment by inhibiting NNMT

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Additional testing may be considered for people with a family history of premature heart disease, metabolic risk, abnormal cholesterol results, known cardiovascular disease, or uncertainty after standard testing: ApoB, Lp(a), and hs-CRP may help reveal particle burden, inherited risk, and inflammation that are not fully captured by LDL cholesterol alone