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Notably, semaglutide treatment correlated with decreased GAL3 levels in the cerebral cortex and improved behavioral outcomes
Rybelsus (semaglutide) is FDA-approved to treat type 2 diabetes, but some providers also prescribe it off label to support weight loss
However, this study did not specify the maximum tolerated PT 141 dosage
This was further supported by experiments in the SAMP8 mouse model of AD, in which liraglutide delayed or halted the decline in memory function along with hippocampal neuronal loss [47]
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