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Research applications Research applications In vitro GHRH receptor and GHSR (ghrelin receptor) binding and signaling assays cAMP/PKA pathway and somatotroph activation studies Cellular secretion and endocrine axis modeling Mechanistic combination and dose-response interaction studies For laboratory research use only
The liver
PubMed 16352683) remains the definitive human pharmacology study: CJC-1295 (with DAC) in 57 healthy adults produced 210 GH elevation and 1.53 IGF-1 elevation sustained for 911 days
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