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Es asimismo muy interesante la capacidad de GLP-1 para inducir distintos efectos, denominados extrapancreticos o extraglucmicos, entre los que se encuentra el retraso en el vaciamiento gstrico, la supresin del apetito y, en modelos in vitro, la inhibicin de la apoptosis de las clulas beta pancrticas y la presencia de efectos de proteccin cardiovascular

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As for the incident patients, an increase from 1.8 patients/1000 inhabitants in 2019 to 7.4 patients/1000 inhabitants in 2023 could be observed (Table 1 (Panel B))

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Manufactured by Novo Nordisk at a list price approaching $1,000 per month, Wegovy was also the drug that most patients associated with the GLP-1 weight loss revolution