Symptoms commonly associated with gastroparesis include postprandial fullness, nausea, vomiting, anorexia and weight loss, with or without abdominal pain
2b, d, 3b, c, d, 4a and Supplementary Figs 5, 6, 7, 8, 9, 10, 13, 14, 15b, c, and 16 are provided as a Source Data file
These drugs influence signaling pathways involved in appetite regulation and the brains reward system, which could help explain the reduced dependence not only on food but also on alcohol
Related mode-of-action work has evaluated changes in body weight, fat mass, lean mass, and feeding behavior in controlled models, helping researchers explore how amylin pathway activation reshapes whole-body metabolic phenotypes [4]
This weight loss is achieved through mechanisms such as appetite suppression, increased satiety, and reduced caloric intake