glp-1 drugs and inflammation Frontiers GLP-1 | Summary

Following the catabolism of glucose in the cytoplasm as part of glycolysis, the generated pyruvate is transported to the mitochondrial matrix, where it feeds into the TCA, undergoing oxidation to reduce NAD + to NADH, which is the main electron donor of the ETC 87

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This ratio of GSH: GSSG is maintained by the action of GSSG reductase, which requires NADPH+ as the reducing cofactor

Nijenbandring de Boer et al., 2014)

Nasal tanners contain a synthetic hormone called melanotan, which mimics the naturally occurring melanocyte-stimulating hormone (MSH) in the body