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Over the past five years, Ive watchedand written aboutthe massive rise in popularity of these medications with a professionally detached mix of curiosity and concern

The swelling typically resolves over 6 to 12 weeks, leaving behind optic atrophy and permanent visual field defects

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Congenital leptin deficiency: diagnosis and effects of leptin replacement therapy

Other factors include: Underlying cause of deficiency : Pernicious anaemia, malabsorption disorders, or dietary insufficiency may affect treatment response Medication use : Metformin and proton pump inhibitors can reduce gastrointestinal B12 absorption (though this does not affect the efficacy of intramuscular injections) Individual variation : Differences in how efficiently your body utilises the injected vitamin Adherence to treatment schedule : Missing injections or delaying maintenance doses can slow recovery Discussing these factors with your healthcare provider helps set realistic expectations for your treatment journey