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Clinical trials have consistently reported a significant improvement of the 6-minutes walking distance test, stair climb power, leg press strength and power on androgen treatment, once again indicating a dangerous liaison between the androgen decline and the loss of skeletal muscle trophism [127, 140]
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Another protective mechanism exerted by exenatide on the endothelium is through its action through opening the KATP channels thus protecting against impairment in endothelium-dependent vasodilatation induced by ischemiareperfusion (IR) injury [64]
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