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Lifestyle changes (principally diet, exercise and behavioural interventions) underpin all treatment algorithms

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[1] [2] Patients should be counseled about the potential risk and instructed to report symptoms of thyroid tumors, including: A lump or swelling in the neck Hoarseness or voice changes Difficulty swallowing Shortness of breath It is important to note that the relevance of rodent C-cell tumor findings to humans remains uncertain

For retatrutide, that is 24 to 30 days at a given dose