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Oxidative Stress Regulation: The 2012 Antioxidant Gene Expression Study Pickarts 2012 analysis GHK-Cu May Prevent Oxidative Stress in Skin by Regulating Copper and Modifying Expression of Numerous Antioxidant Genes (DOI: 10.3390/cosmetics3010026, accessible via PubMed Central) addressed a mechanistic paradox: how can a copper-containing compound function as an antioxidant when copper ions are notorious Fenton reaction catalysts

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Zhou, X., Cao, Q., Orfila, C., Zhao, J., & Zhang, L