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In obese patients, acipimox can inhibit adipose tissue lipolysis by activating protein upregulated in macrophage by INF- (PUMA-G) (also known as the hydroxycarboxylic acid receptor 2 [HCA2] and GPR109a) receptors
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Feng R, Shou JW, Zhao ZX, He CY, Ma C, Huang M, et al
Understanding these metabolic mechanisms may pave the way for more effective and personalized treatment strategies for IPF
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