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Further studies showed that AZ3451, an antagonist of PAR2, prevented the IL-1-induced inflammatory cytokines release, catabolic gene expression, senescence, and apoptosis in chondrocytes

Involvement of the Nrf2 pathway in the regulation of pterostilbene-induced apoptosis in HeLa cells via ER stress

J Immunol, 2011

The control HGF without the wash-out step ( black bars 2 ) presented higher indices than the levels of regular control HGF at both HGF doses (also see gray bars 3 with wash-out step)