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Guidelines on Second-and Third-Line Medicines and Type of Insulin for the Control of Blood Glucose Levels in Non-pregnant Adults With Diabetes Mellitus

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This combination has been shown to produce 2-5 greater GH release than either compound alone

This reduction in non-exercise activity thermogenesis (NEAT)the calories burned through daily movementcan significantly impact total energy expenditure

Primary care relevance: Providers will soon be able to prescribe the higher dose, but should counsel patients about the potential for more gastrointestinal side effects and dysaesthesia