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What I think is unique and key for MET-097i is the differentiated linker and fatty acid binding to the C-terminus that allows for albumin binding with or without GLP-1R binding
The reasons for this arent totally clear for instance, there are more young adults living with their parents these days (a potential buzzkill, depending on the circumstances)
By day 0, this parameter did not differ among the five groups (Fig
It is not magic but it helps
( i ) Quantification of H2AX foci in cells expressing empty vector or CCNE1 transduced with shRNAs targeting TMLHE alone (shTMLHE) or supplemented with propionylcarnitine or butyrylcarnitine (n = 3 technical replicates representative from 2 independent experiments in each cell line)
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