The classic symptoms of holocarboxylase synthetase deficiency are hypotonia, lethargy, seizures, metabolic acidosis, vomiting, hyperammonemia, developmental delay, skin rash, and alopecia
Medications like antihistamines and nasal sprays may temporarily relieve symptoms, but they don't address the root cause
Under Prop 215, we had a very large existing market in place that until 2018 was mostly unregulated
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