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Research has explored its activity in collagen production, tissue repair, antioxidant pathways, and cellular protection
Its binding to VMAT2 is very strong, making it's effect appear irreversible, with trace amounts of the drug remaining bound to vesicular membranes for many days, and its clinical effects lasting many days to weeks, and may persist until new transporter proteins are synthesized (German et al, 2015
The clinical trial protocols that showed the best results used treatment cycles with rest periods in between
Authors contributions Herry Sonjaya, Erni Damayanti, and Hikmayani Iskandar designed the study and wrote the draft article
Exosomes-shuttled lncrna snhg7 by bone marrow mesenchymal stem cells alleviates osteoarthritis through targeting mir-485-5p/fsp1 axis-mediated chondrocytes ferroptosis and inflammation
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