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While drugs like Ozempic and Wegovy offer powerful benefits for weight management, they also introduce challenges

They lower cortisol (your stress hormone), support insulin sensitivity, and reduce low-grade inflammation which means: Fewer crashes and cravings Less belly fat storage Better sleep and recovery For women in their 40s and 50s on the Josie program, this shift often brings more energy and better sleep too

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The outcomes were changes in weight, body mass index (BMI), waist circumference (WC), glycemia, blood pressure, and lipid profiles

Arthritis Care & Research, 65 (1), 1522