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According to the company, the compound demonstrated approximately 15% weight loss in preclinical testing, compared with roughly 9% observed with liraglutide, while food intake reductions reached approximately 39% versus around 20% for the comparator
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28.7% 7.8%), but they experienced more severe long-term weight regain (median regain: 14.2 kg vs
& Baruch, A
When semaglutide is discontinued, this reduced metabolic rate remains, but the appetite suppression that helped you maintain a caloric deficit disappears, creating conditions favorable for weight regain
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