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Metformin: an old but still the best treatment for type 2 diabetes
Glutathiones reduced form (GSH): Carries an extra electron (hydrogen) Donates hydrogen (electron) to inflammation-causing free radicals to neutralize their effect Glutathione peroxidase enzyme Requires selenium Converts two hydrogen peroxides into two water molecules Glutathiones oxidized form (GSSG): State of glutathione after losing its electron Forms a disulfide bridge between two glutathione molecules Glutathione reductase enzyme Glutathione can be recycled back to its reduced form using NADPH (reducing agent, electron donor)
Additionally, the inability to synthesize tyrosine will make this a conditionally essential amino acid and potentially negatively impact the synthesis of downstream compounds illustrated in figure 4.2
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