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Consequently, PGA formation constitutes an overflow pathway that becomes prominent only when normal glutathione homeostasis is compromised, making it a valuable marker of impaired cellular antioxidant capacity and metabolic stress

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In our study, 51 participants who received neoadjuvant therapy were categorized as the sensitive group (patients with pCR and pPR, n = 30) or the resistant group (patients with pNC, n = 21) (Table 2)

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