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We are grateful to Marcel Mettlen and Abhijit Bugde (UTSW) for microscopy training

A 2024 study led by Wang, Volkow, and colleagues examined two cohorts totaling over 682,000 individuals with either obesity or type 2 diabetes and found the risk of new alcohol use disorder diagnoses was about 50% lower among those taking semaglutide compared to other anti-obesity or diabetes medications (Wang et al., 2024a)

The pharmaceutical companies that developed these drugs spent years working out the eventual FDA-approved doses of their active ingredients (semaglutide for Ozempic and Wegovy

The control group (CON group

Wegovy is the FDA-approved semaglutide formulation for weight loss