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GLP-1 Receptor Agonists: From Diabetes Drugs to a New Era of Metabolic & Systemic Medicine GLP-1 receptor agonists (GLP-1RAs) represent one of the most transformative therapeutic advances in modern medicine
Many patients report substantial improvement or complete resolution of initial symptoms after several weeks of maintaining a stable dose, though individual experiences vary widely
are overweight or have obesity, a condition linked to serious health risks such as T2D, cardiovascular disease (CVD), and obstructive sleep apnea (OSA)
In 1973, John Brown discovered the glucose-dependent insulinotropic polypeptide (GIP) employing peptide purification and protein sequencing, it was shown to have an incretin effect, increasing Insulin release triggered by glucose intake after oral administration [11]
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