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Not intended to diagnose, treat, cure, or prevent any condition.

However, these drugs may also be prescribed to adults with a BMI of 27 or higher if they have other health conditions such as type 2 diabetes or high cholesterol

Key risks include bupropion's seizure threshold lowering effect, additive gastrointestinal side effects from both medications, cardiovascular effects including increased heart rate and blood pressure, and potential psychiatric symptoms

Both influence electrolyte balance and blood pressure, producing a cumulative effect

However, altered metabolic pathways may also stimulate the formation of characteristic protein aggregates in ALS and FTLD (Fig