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| 03.20.26 | 7 min read
K.Abdul AzzizS
Applications have been suggested for muscle, tendon, nerve regeneration, and brain health
Specific examples of methylation in detoxification: Arsenic detoxification requires sequential methylation: arsenite to monomethylarsonic acid to dimethylarsinic acid (the excretable form), catalyzed by arsenic methyltransferase (AS3MT) using SAM-e R Mercury undergoes methylation by gut bacteria, converting inorganic mercury to more toxic methylmercury (this is detrimental methylation, not detoxification) R COMT methylation of 4-hydroxy catechol estrogens prevents them from forming reactive quinones that generate ROS and DNA damage R 6
Thus, assuming comparable glomerular filtration rate among groups, urinary creatinine was used as a normalization element for urinary Kim-1 values
