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The mechanism is systemic rather than tissue-targeted, distinguishing this class from the direct-acting tendon peptides

PMID: 23755725 Secondary VEGF / VEGFR2 Signaling VEGF-Mediated Angiogenesis Pathway Research has demonstrated that BPC-157 upregulates VEGFR2 expression in endothelial cell models

Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice

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