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Conclusions Amylin, a neuroendocrine hormone co-secreted with insulin, is deficient in individuals with diabetes and plays an important role in postprandial glucose homeostasis by suppressing glucagon secretion and delaying gastric emptying
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With its multi-receptor mechanism, tirzepatide provides a spectrum of health benefits beyond weight loss for individuals with multifaceted metabolic conditions
Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate
Gastrointestinal side effects: Nausea, vomiting, and diarrhoea which are frequently reported in trial data can lead to dehydration and electrolyte imbalances, both of which may contribute to fatigue
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