If history has taught us anything, its that people will always look for path of least resistance
Regarding diabetic complications: 11.2% Diabetic retinopathy (using a portable fundus camera), 14.41% diabetic kidney disease (using CKD-EP), 26.34% diabetic peripheral neuropathy (neuropathic symptom score and Semmes-Weintein monofilament), 9.66% cardiovascular autonomic neuropathy (spectral analysis and Ewing tests) and 11.75% cognitive decline (using Minimental)
Goal intensity Aggressive goals justify more intensive protocols
However, despite the anti-diabetic and anti-obesity functions, of these dual and triple agonists, the long-term safety, cardiovascular, and renal benefits of these multi-target therapies need further validation
Collagen production is ramping up, though structural changes in the skin matrix take longer to become obvious