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Research indicates that the peptide may interact selectively with growth hormone secretagogue receptors while exhibiting relatively narrow receptor specificity compared with earlier compounds in the same category
DeFronzo RA, Triplitt CL, Abdul-Ghani M, Cersosimo E
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In the only direct head-to-head trial, semaglutide 2.4 mg led to 15.8% average weight loss compared with 6.4% with liraglutide 3.0 mg over 68 weeks
Walker C, Aitken JF, Amarsingh GV et al (2025) Amylin: emergent therapeutic opportunities in overweight, obesity and diabetes mellitus
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