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These guidelines synthesize evidence from multiple trials and provide recommendations on patient selection, dosing, monitoring, and combination therapy strategies
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Each opening exposes the vial to a 5-10C temperature spike
A patient satisfies the diagnostic criteria for FMS if the following 3 conditions are met: Although the precise mechanisms contributing to the pathophysiology of FMS remain to be fully elucidated, it is thought that patients with fibromyalgia have impaired endogenous analgesic systems, in particular suboptimally functioning descending inhibitory pathways, which normally function to ameliorate pain as well as abnormal pain processing
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