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In preclinical models, nanovaccines have been associated with increased antigen-specific CD8 T cells, memory or tissue-resident T-cell populations and improved tumor control, particularly when combined with immune checkpoint inhibitors [81, 83]
Supplementary Table 2)
The mechanism is thought to relate to glucagon-receptor activation and energy-substrate shifts, but it is not fully characterized
References: A Brave New World: Therapeutic Area Deep Dives on Obesity This blog is part of a new series exploring a range of topics in the obesity market, including: market size and scope, impact of payer controls, activity in non-traditional channels, patient behavior, GLP-1 impact, HCP responses, the policy landscape, pharmacy economics, and the outlook for the future of GLP-1
GWAS of GLP1 medication side effects We performed a GWAS of 11 side effect phenotypes that contrast patients with moderate or severe side effects to those who experienced mild or no side effects
